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The acids that may be used to prepare pharmaceutically acceptable acid addition salts of the tetracycline compounds of the invention that are basic in nature are those that form non-toxic acid addition salts, ie, salts containing pharmaceutically acceptable anions, such as the hydrochloride, hydrobromide, hydroiodide, nitrate, sulfate, bisulfate, phosphate, acid phosphate, isonicotinate, acetate, lactate, salicylate, citrate, acid citrate, tartrate, pantothenate, bitartrate, ascorbate, succinate, maleate, gentisinate, ftumarate, gluconate, glucaronate, saccharate, formate, benzoate, glutamate, methanesulfonate, ethanesulfonate, benzenesulfonate, p-toluenesulfonate and palmoate [ie, 1,1′-methylene-bis-(2-hydroxy-3-naphthoate)]salts. • Fluoxetine : May enhance the adverse/toxic effect of Tricyclic Antidepressants? The type of solution and the time they should be soaked for will be advised by your dentist. • The safety of this medicine during pregnancy has not been fully establishedThe manufacturer recommends it should only be used in pregnant women if the expected benefit to the mother is greater than any possible risk to the developing baby? You must gradually reduce the dose or you may get severe side effects?

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